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Following syndromes are associated with diabetes mellitus
S. No. |
SYNDROMES |
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CLINICAL FEATURES |
1. |
ALSTRUM'S SYNDROME |
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Diabetes mellitus with Retinitis pegmentosa, nystagmus, loss of central vision, Nerve deafness, obesity gonadal failure. |
2. |
ATAXIA TELANGIECTASIA |
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Diabetes mellitus, Cerebellar ataxia, telangiectasia. |
3. |
B1EMOND SYNDROME |
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D.M., obesity, Sec. Hypogonadism polydctyly, Iris colobomat. |
4. |
CUSHING'S SYNDROME |
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Muscle weakness, Moon facies, Buffalohurnp, FMigabilitv, osteoporosis, Hypertension, Psychosis. |
5. |
CANDIDIASIS SYNDROME (ENDOCRINOPATHY) |
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I.D.D.M., Childhood onset Monilial Infection, Addi&on Disease, Hypotension, Hyperpigmentation of Mucosal & Cutaneas surface. |
6. |
DOWN'S SYNDROME |
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D.M., Mental Retardation, Muscular Hypotonia, Brachycephaly, oblique, orbital, fissure, Flat nasal bridge folded ears, Nystagmus, narrow palate, short- broad hand, shortneck. |
7. |
SCHMIDT SYNDROME |
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D.M., Adrenal Insufficiency, thyroiditis, gonadal failure. |
8. |
HYPORENINEM1C HYPOLDOSTERONISM SYNDROME |
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D.M., mild renal failure, Hyperkalemia, metabolic acidosis. |
9. |
SYNDROME -X |
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D.M. Hypertension, high L.D-L., Low HDL Atheroma formation, obesity. |
10. |
PRIMARY HYPOTHYRODISM (HASIMOTO'S THYRODITIS) |
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D.M., with Sign & Symptoms of Hypothyroidism. |
11. |
WOLFRAN'S SYNDROME |
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I.D.D.M., Diabetes Insipidus, optic atrophy, Nerve deafness |
12. |
OBESITY-HYPOGONADISM |
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D.M., obesity, Hypogonadism |
13. |
LAURANCE -MOON-BIEDLY Synd |
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D.M., retinitis pigmantosa, polydactyly Mental Retardation, obesity, renal anomaly Hypogonadism. |
14. |
FANCONI SYNDROME |
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D.M., with short stature, Bone marrow Hypoplasia, Abnormal Skin pigmentation, Radius Malformation. |
15. |
15. WERNER SYNDROME |
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D.M., premature ageing of all organ system, alrophic Skin, Cataract, Early Osteoporosis, gonadal atrophy, pappilary carcinome thyroid. |
16. |
PRADER-WILLI SYNDROME |
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D.M., obesity, Hypogonadison, Hypotension Mental Retardation. |
17. |
SIPPLE SYNDROME |
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DM, with pheochromocytoma like HT., paltitation, ABd pain, Profuse sweating headache, medullary Thyroid carcinome |
18. |
PINEAL HYPERTROPHY SYNDROME |
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D.M., Malformed teeth, Dry Skin, thick nail, Hirsutism, Sexual Precosity Enlargement of Ext. gentalia.
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19. |
ROBBON-MENDENHA LL SYNDROME |
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D.M., Dental Dysplasia, dystrophic nail, Pre mature puberty, Acanthosis Nigrans. |
20. |
LEPRECHAUMISM SYNDROME |
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D.M., Elfin appearance of the face, Hirsutism, absence of sub cutaneous fat. Thickened Skin. |
21. |
KLINEFELTER SYNDROME |
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D.M., small firm testes, tall stature, obesity, Gyneomestia, Mental deformity azoospermia, varicose vein. |
22. |
ACANTHOSES NIGRANS (TYPE A SYNDROME). |
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Obesity, D.M., poly cystic ovaries cushings synd. acromegaly, Localised area of grey brown Hyper pigmentation in post region of neck & axilla. |
23. |
GLUCAGONOMA SYNDROME |
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D.M-, anemia, Hypokalemia, Necrolytic, Migratory erythema. |
24. |
CONG BERARDJNELLI-SEIP SYND (CONGLIPODYSTROPHY) |
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D.M., Sclerosis, Cystic angiomatosis Mental Retardation, clitoromegaly, polycystice ovaries, penile Hypertrophy cardiomegaly, hepatomegaly, cirrhosis lynphaadenopathy, Acanthosis nigracans Hypertrichosis, Goiter, Renal Hypertrop. |
25. |
LAWRANCE SYNDROME (ACQUIRED LIPODYSTROPHY) |
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D.M., Feature same as above. Develop after some illness like measles, Chicken pox, painful nodular swelling. |
26. |
ACROMEGALY |
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D.M., Proximalmvopathy, osteo arthritis H.T., cardiomegaly, LVH, tongue Enlargement, goiter, visual field defect, increased heel pad, acanthosis Nigrans frontal bossing, carpa! -runnel Syndome. |
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